Chicago · İstanbul · İzmir

Genomic data, read with CLARITY.

Clarity Genomics is a Chicago-based AI-assisted bioinformatics, comprehensive genomic profiling (CGP) and oncology company. Through our STAR framework we connect physicians and genetic centers abroad with CLIA-certified US reference laboratories, and turn raw results into reports clinicians can act on.

Clarity Genomics logo: Specialized Translational Analysis & Reporting — Chicago | İzmir

The framework

STAR: from specimen to signed report

Specialized Translational Analysis & Reporting. Four disciplines that keep every case consistent, traceable and clinically useful.

S

Specialized

Test selection matched to the clinical question: NIPT, hereditary panels, exome and tumor profiling.

T

Translational

Variant findings placed in clinical context using current ACMG/AMP and AMP/ASCO/CAP classification standards.

A

Analysis

Bioinformatics review of the reference laboratory's data: coverage, quality metrics and variant evidence.

R

Reporting

Localized, bilingual reports written for the treating physician, delivered through the partner center.

Services

What we do

INTERPRETATION

Variant interpretation & clinical reporting

Structured, evidence-graded reports for germline and somatic findings, with plain-language summaries for clinicians.

BIOINFORMATICS

Pipeline development

Design and automation of localized reporting pipelines for NIPT and genomic profiling, built with global laboratory partners.

COORDINATION

International specimen coordination

Consent, chain-of-custody and logistics from partner centers to independent CLIA-certified US reference laboratories.

ONCOLOGY

Oncology genomics review

Tumor profiling results reviewed alongside our oncology advisor, with therapy-relevant findings highlighted for the treating team.

Products

The CLARiTY test portfolio

Prenatal screening

CLARiTYnipt

Non-invasive prenatal screening from cell-free DNA in maternal blood.

  • Trisomies 21, 18 and 13
  • Sex chromosome aneuploidies
  • From 10 weeks of gestation
  • Screening test: high-risk results need diagnostic confirmation
Whole-exome sequencing

CLARiTYwes

Sequencing of the protein-coding regions of roughly 20,000 genes for suspected inherited disorders.

  • Rare and undiagnosed disease
  • Proband or trio analysis
  • ACMG/AMP variant classification
  • Bilingual interpretive report
Whole-genome sequencing

CLARiTYwgs

Sequencing across coding and non-coding regions in a single test.

  • SNVs, indels, CNVs and structural variants
  • Mitochondrial genome
  • Broadest germline coverage
  • ACMG/AMP variant classification
Comprehensive genomic profiling

CLARiTYcgp

Tumor profiling of hundreds of cancer-related genes to support therapy selection.

  • SNVs, indels, copy-number changes and fusions
  • TMB and MSI status
  • Therapy and clinical-trial matching
  • Reviewed with our oncology advisor

All CLARiTY tests are performed by independent CLIA-certified reference laboratories and ordered by the patient's licensed physician.

How it works

One case, five steps

  1. Order and consent

    The patient's licensed physician at a partner center selects the test and obtains informed consent.

  2. Specimen logistics

    The specimen travels under documented chain of custody to Clarity Genomics in Chicago.

  3. Laboratory testing

    An independent CLIA-certified reference laboratory performs the analysis.

  4. STAR review

    Our team reviews the data and prepares a localized interpretive report.

  5. Report to the physician

    The final report returns to the treating physician, who discusses it with the patient.

Clarity Genomics LLC does not operate a clinical laboratory and does not perform testing. All laboratory testing is performed by independent, CLIA-certified reference laboratories.

Network

Two cities, one standard

41.88° N · 87.63° W

Chicago, Illinois

Headquarters. Coordination, bioinformatics and reporting.

38.42° N · 27.14° E

İzmir, Turkey

İzmir Genetik, a licensed genetic evaluation center founded in 2015.

People

Advisory Committee

Oncology Advisor

Prof. Dr. Tarık Salman, MD PhD

Professor of Medical Oncology and Internal Medicine with more than two decades of clinical and academic experience in solid tumors and precision oncology. He advises Clarity Genomics on tumor profiling and the clinical use of oncology genomic reports.

Medical oncologyBreast, lung & GI cancersPrecision oncology
Full biography

Prof. Dr. Tarık Salman is a Professor of Medical Oncology and Internal Medicine. After completing his medical education and internal medicine specialization, he completed subspecialty fellowship training in Medical Oncology at leading university medical faculties and tertiary oncology research centers. Committed early in his career to international standards and frontier cancer management strategies, he also completed an observership program at Memorial Sloan Kettering Cancer Center (MSKCC), building a robust foundation in clinical and translational research.

With over two decades of clinical, academic and leadership experience in oncology, Prof. Salman actively contributes to leading international scientific bodies, including the American Society of Clinical Oncology (ASCO) and the European Society for Medical Oncology (ESMO), as well as specialized societies in geriatric and Mediterranean oncology. His clinical and clinical-trial expertise spans complex solid tumors—most notably breast, lung and gastrointestinal malignancies—with a dedicated focus on targeted systemic therapies, novel immunotherapeutic modalities and the real-world value of multidisciplinary tumor boards.

At the forefront of oncology’s paradigm shift toward individualized care, Prof. Salman is a dedicated advocate for precision oncology, championing the seamless integration of comprehensive genomic profiling (CGP), multi-omics diagnostics, and biomarker-driven therapy selection into daily clinical workflows. As a seasoned clinical oncologist, academician, and healthcare opinion leader, he provides the crucial bedside-to-bench perspective needed to bridge high-throughput omics platforms, AI-driven pathology diagnostics, and novel pharmaceutical pipelines directly to patient-centered clinical efficacy, toxicity management, and cross-border innovation. With this goal in mind, he recently started utilizing his expertise in his Clinical Research Organization, Galenos CRO & Bioinformatics.

Advisory Committee

Further members to be announced

The committee brings clinical, laboratory and regulatory expertise from the US and Turkey to review STAR reporting standards.

Contact

Work with us

For genetic centers, clinicians and laboratories interested in the STAR framework.

Office
Chicago, Illinois, USA
Email
hummolgen@gmail.com
Languages
English · Türkçe